Class: Rev-ErbAα Agonist
What: SR-9009 increases exercise capacity, and metabolism.
How: SR-9009 is very similar in action and effect to GW-501516 (which acts as a PPAR-delta agonist). Rev-ErbAα has roles in the body which influence lipid and glucose metabolism,the production of fat-storing cells and the response of macrophages (cells that remove dying or dead cells) during inflammation. Activation of Rev-ErbAα with SR-9009 has been demonstrated, in studies, to increase metabolic activity in skeletal muscle. The tested animals increased their running capacity (in time and distance by 50%.